Abstract

The coumarin derivatives 2 -acetyl 3 H -benzo[f]chromen -3 -one and 3 -acetyl 7 -(diethylamino)-2H -chromen -2 -one) are high-performance fluorescent probes. Their high fluorescence quantum yields enable them to be very bright and efficient in their light emission, and hence make them ideal in imaging and sensing. The unique property of them is that they are versatile: their Stokes shift depends on solvent polarity, and the emission wavelength varies substantially with the polarity around them. This along with a high dipole moment makes the molecules very sensitive reporters of the local environment, capable of marking subtle changes in ion concentration, molecular interactions or cellular microviscosity. These characteristics allow the entry into a variety of practical applications. They have the capability of imaging biological processes and structures with minimal background in biological imaging. They have a high level of response to environmental signals such that they are promising agents in the detection of ions, small molecules, or biomolecules in analytical chemistry. Concisely, the combination of the bright fluorescence, the polarity-tuned emission, and a large dipole moment makes them potent instruments in the further development of sensing technologies as well as the development of biological imaging studies.

Biography

Dr. Varsha V Koppal, has completed her Ph.D in 2019 from Visweshwarayya Technological University, Belgaum. She is an active researcher in the field of Molecular spectroscopy, having published more than 21 papers in reputable journals, and serves as an assistant professor in the Department of Physics at KLE Technological University, Hubballi, Karnataka, India.