Dr. Zaineb Hamzaoui, a prominent microbiologist, holds a Ph.D. from the Faculty of Sciences in Tunis, Tunisia, specializing in antimicrobial resistance mechanisms. With expertise in molecular biology and genomic sequencing, particularly in SARS-CoV-2 and bacterial studies, she currently serves as a postdoctoral researcher at the Faculty of Medicine in Tunis. Additionally, she contributes to academia as a part-time lecturer. Previously, Dr. Hamzaoui collaborated with the World Health Organization during the COVID-19 pandemic, aiding in the diagnosis and sequencing of SARS-CoV-2 in Tunisia. Her dedication to scientific inquiry and public health is unparalleled.

Abstract
In recent years there has been a progressive increase in the prevalence of neurodevelopmental disorders. Therefore, from environmental epidemiology and public health there is a growing concern about the gene-environment interaction, about the environmental factors that may be contributing to the increase of neurodevelopmental disorders, with the purpose of establishing adequate prevention and public health strategies. The proper functioning of thyroid hormone during pregnancy is essential for proper fetal neurodevelopment, mild, even subtle, deficits of thyroid hormone during pregnancy due to iodine deficiency, environmental pollutants, or endocrine disruptors, even at low doses, are associated with neurdevelopmental disorders.The purpose of the present research is to carry out a comprehensive review artitles indexed, between 2000 and 2019, in electronic databases PubMed and Medline of endocrine disruptors and neurodevelopmental disorders, focusing on four of the most studied pollutants to which pregnant women and children are exposed, such as polychlorinated biphenyls (PCBs), polybrominated diphenyl ethers (PBDEs), bisphenol A (BPA), and pesticides, analyzing their effect on the molecular mechanism of maternal and infant thyroid function essential for infant neurodevelopment and whose alteration has been associated with different neurodevelopmental disorders. This study results provide scientific evidence of the association that exists between these environmental neurotoxins and various neurodevelopmental disorders and contributes to the research, as it helps to understand the role played by environmental factors in the pathogenesis of neurodevelopmental disorders and autism, allowing the establishment of prevention and intervention strategies. Appropriate measures around proper regulation, public health, environmental policies and clinical practice are discussed.

Abstract 
Background: Internet use has been widespread in the past decades and its potentials for the
development of symptoms of addictions have been recognized from its early days. So far, the
problematic internet use (PIU) has been associated with the impulsivity as a personality trait,
depressive symptoms, low self-esteem and low physical activity. The aim of this study was to
examine the association between PIU and social, lifestyle and health status characteristics among
the Medical students in Serbia.
Methods: This was a cross-sectional study that was conducted during November of 2023 among the
Medical students at two Universities in Serbia, Belgrade and Kosovska Mitrovica, total of 436. The
study included all fifth-year students at both Universities and employed questionnaire to examine
their social characteristics (age, sex, place of residence, financial status), health status
characteristics (self-rated health, depressive symptoms- examined using the Patient Health
Questionnaire-9-PHQ-9), and state impulsivity (using the State impulsivity scale) and PIU, using
the PIU scale. Based on the score on the PIU scale (cutoff score of 41), students were classified as:
with and without PIU.
Results: The average score on the Problematic internet use scale was 32.13±13.14, the average
score on the obsession scale was 9.53±4.82, and on the neglect scale was 11.05±4.86, while the
average score on the loss of control scale was 11.55±5.14. Total of 22% of the participants were in
the group for Problematic Internet Use (score >41 on PIU scale). Multivariate logistic regression
analysis showed the association between the PIU and self-rated health status as poor (OR: 3.70,
95% CI: 1.04-13.12) and score on impulsivity scale (OR: 1.05, 95% CI: 1.03-1.08).
Conclusion: The students with the scores indicative of PIU were more likely to assess their health as
poor, and to have higher scores on impulsivity scale.