1.0Cognition Conferenceshttps://cognitionconferences.com/immunologyCognition Conferenceshttps://cognitionconferences.com/immunology/author/cogn-3012/rich600338<blockquote class="wp-embedded-content" data-secret="XTTlbKvLLl"><a href="https://cognitionconferences.com/immunology/committee/lourdes-isaac/">Lourdes Isaac</a></blockquote><iframe sandbox="allow-scripts" security="restricted" src="https://cognitionconferences.com/immunology/committee/lourdes-isaac/embed/#?secret=XTTlbKvLLl" width="600" height="338" title="“Lourdes Isaac” — Cognition Conferences" data-secret="XTTlbKvLLl" frameborder="0" marginwidth="0" marginheight="0" scrolling="no" class="wp-embedded-content"></iframe><script type="text/javascript"> /* <![CDATA[ */ /*! This file is auto-generated */ !function(d,l){"use strict";l.querySelector&&d.addEventListener&&"undefined"!=typeof URL&&(d.wp=d.wp||{},d.wp.receiveEmbedMessage||(d.wp.receiveEmbedMessage=function(e){var t=e.data;if((t||t.secret||t.message||t.value)&&!/[^a-zA-Z0-9]/.test(t.secret)){for(var s,r,n,a=l.querySelectorAll('iframe[data-secret="'+t.secret+'"]'),o=l.querySelectorAll('blockquote[data-secret="'+t.secret+'"]'),c=new RegExp("^https?:$","i"),i=0;i<o.length;i++)o[i].style.display="none";for(i=0;i<a.length;i++)s=a[i],e.source===s.contentWindow&&(s.removeAttribute("style"),"height"===t.message?(1e3<(r=parseInt(t.value,10))?r=1e3:~~r<200&&(r=200),s.height=r):"link"===t.message&&(r=new URL(s.getAttribute("src")),n=new URL(t.value),c.test(n.protocol))&&n.host===r.host&&l.activeElement===s&&(d.top.location.href=t.value))}},d.addEventListener("message",d.wp.receiveEmbedMessage,!1),l.addEventListener("DOMContentLoaded",function(){for(var e,t,s=l.querySelectorAll("iframe.wp-embedded-content"),r=0;r<s.length;r++)(t=(e=s[r]).getAttribute("data-secret"))||(t=Math.random().toString(36).substring(2,12),e.src+="#?secret="+t,e.setAttribute("data-secret",t)),e.contentWindow.postMessage({message:"ready",secret:t},"*")},!1)))}(window,document); //# sourceURL=https://cognitionconferences.com/immunology/wp-includes/js/wp-embed.min.js /* ]]> */ </script> https://cognitionconferences.com/immunology/wp-content/uploads/2026/03/Konstantinos-Protopapas.png200240Leptospirosis is one of the major zoonotic diseases worldwide, most frequently found in tropical and subtropical countries, especially in regions with poor sanitation. It is a disease with over one million new cases each year, and is fatal in 5-10% of them.Pathogenic leptospires are quite resistant to the action of the Complement System, while non-pathogenic leptospires die rapidly. We investigated the mechanisms by which these bacteria are able to evade this system, which bacterial proteins are involved in this evasion, and interactions between Complement System proteins and leptospiral proteins. In parallel, we also developed experimental models where vaccine candidates are being tested, with the aim of proposing more efficient prophylactic measures for the control of this zoonosis.