Abstract

INTRODUCTION: The medical chestnut honey is not act only as an antiseptic, it also significantly cleanses and debride the wound in the inflammation phase (saturated sugar solution generates osmotic pressure in the wound, stimulating autolytic debridement; glucose oxidase enzyme help activate protease debridement and promotes antimicrobial and anti-inflammatory activity; kynurenic acid destabilises and inhibits biofilm formation), promotes granulation and stimulates epithelialization (high levels of calcium manganese, zinc, potassium, and proline stimulate granulation and epithelization; high levels of polyphenols and flavonoids have antioxidative activity).

METHODES:
Study 1: To evaluated effects on healing and pain in 19 C2-3 VLUs (venous leg ulcer) treating with medical chestnut honey alginate verssus16 C3 VLUs treating with PHMB foam. In the first week of the study, we proved that alginate dressing with medical chestnut honey cleansed the wound bed faster than polyhexanides, which showed its high efficiency in treating infected venous leg ulcers.

Study 2: We usually use foams to treat wounds once wound bed is clean, that is, for the granulation phase. In our case study, at 7 VLUs, we used medical chestnut honey foam on ulcers whose wound beds were classified as C3 by Falanga´s classification. Within 14 days, the wound beds of all wounds became B3. Medical chestnut honey foams have also been shown to be suitable for debridement and promoting granulation.

Study 3: In case study we treated the patient with VLU on all circumferences of the lower two thirds of the left shin, where wound bed was A2 according to Falanga classification. After 14 days of applied alginate dressing with medical chestnut honey on the half of VLU and hydrofiber dressing with silver to the other half of VLU, the erosions epithelized and healed faster on the side where we used medical chestnut honey.

RESULTS: Medical chestnut honey alginate is an appropriate choice for infected wounds, for fibrin debridement in the inflammatory phase and medical chestnut honey foam accelerates granulation and epithelialization of ulcers.